
An Introduction to Medicinal Chemistry
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An Introduction to Medicinal Chemistry
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Standort: Egg Harbor Township, New Jersey, USA
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eBay-Artikelnr.:177627193828
Artikelmerkmale
- Artikelzustand
- Release Year
- 2017
- ISBN
- 9780198749691
Über dieses Produkt
Product Identifiers
Publisher
Oxford University Press, Incorporated
ISBN-10
0198749694
ISBN-13
9780198749691
eBay Product ID (ePID)
239487912
Product Key Features
Edition
6
Book Title
Introduction to Medicinal Chemistry
Number of Pages
888 Pages
Language
English
Topic
Chemistry / Clinical, Chemistry / General
Publication Year
2017
Illustrator
Yes
Genre
Science
Format
Trade Paperback
Dimensions
Item Height
1.2 in
Item Weight
56.4 Oz
Item Length
7.5 in
Item Width
10.4 in
Additional Product Features
Dewey Edition
23
Reviews
"It is by far the best book on the market for medicinal chemistry and drug discovery." --Professor Steven Bull, University of Bath, 'It is by far the best book on the market for medicinal chemistry and drug discovery.' Professor Steven Bull, University of Bath'Summarizes the chemistry of medicinal agents in a manner that easily facilitates understanding of the core principles in the context of pharmacological drug action and clinical therapeutics.' Professor John Marriott, University of Birmingham
TitleLeading
An
Dewey Decimal
615.19
Table Of Content
1. Drugs and drug targets - an overviewPart A Drug targets - structure and function2. Protein structure and function3. Enzymes: structure and function4. Receptors: structure and function5. Receptors and signal transduction6. Nucleic acids: structure and functionPart B Pharmacodynamics and pharmacokinetics7. Enzymes as drug targets8. Receptors as drug targets9. Nucleic acids as drug targets10. Miscellaneous drug targets11. Pharmacokinetics and related topicsCase study 1: StatinsPart C Drug discovery, design, and development12. Drug discovery: finding a lead13. Drug design: optimizing target interactions14. Drug design: optimizing access to the target15. Getting the drug to marketCase study 2: The design of ACE inhibitorsCase study 3: Artemisinin and related antimalarial drugsCase study 4: The design of oxamniquinePart D Tools of the trade16. Combinatorial synthesis17. Computers in medicinal chemistry18. Quantitative structure-activity relationships (QSAR)Case study 5: De novo design of a thymidylate synthase inhibitorPart E Selected topics in medicinal chemistry19. Antibacterial agents20. Antiviral agents21. Anticancer agents22. Cholinergics, anticholinergics, and anticholinesterases23. Drugs acting on the adrenergic nervous system24. Opioid analgesics25. Antiulcer agents26. Cardiovascular drugsCase Study 6: Steroidal anti-inflammatory agentsCase Study 7: Design of a novel antidepressantCase Study 8: The design and development of aliskirenCase Study 9: Factor Xa inhibitorsCase Study 10: Reversible inhibitors of HCV NS3-4A proteaseAppendices
Synopsis
For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market? An Introduction to Medicinal Chemistry , sixth edition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Part one of the book introduces the principles of drug action via targets such as receptors and enzymes. The book goes on to explore how drugs work at the molecular level (pharmacodynamics), and the processes involved in ensuring a drug meets its target (pharmacokinetics). Further sections cover the processes by which drugs are discovered and designed, and what has to happen before a drug can be made available to the public. The book concludes with a selection of current topics in medicinal chemistry, and a discussion of various key drug groups. The subject is brought to life throughout by engaging case studies highlighting particular drugs and the stories behind their discovery and development. The Online Resource Centre features: For students: DT Multiple Choice Questions to support self-directed learning DT Web articles describing recent developments in the field and further information on topics covered in the book DT Journal Club to encourage students to critically analyse the research literature DT Molecular Modelling Exercises, with new exercises in Chem3D DT New assignments to help students develop data analysis and problem solving skills For registered adopters of the book: DT A test bank of additional multiple-choice questions, with links to relevant sections in the book DT Answers to end-of-chapter questions. DT Figures from the book, ready to download. DT Power Point slides to accompany every chapter in the book., For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market?An Introduction to Medicinal Chemistry, sixth edition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Part one of the book introduces the principles of drug action via targets such as receptors and enzymes. The book goes on to explore how drugs work at the molecular level (pharmacodynamics), and the processes involved in ensuring a drug meets its target (pharmacokinetics). Further sections cover the processes by which drugs are discovered and designed, and what has to happen before a drug can be made available to the public. The book concludes with a selection of current topics in medicinal chemistry, and a discussion of various key drug groups. The subject is brought to life throughout by engaging case studies highlighting particular drugs and the stories behind their discovery and development.The Online Resource Centre features: For students:* Multiple Choice Questions to support self-directed learning * Web articles describing recent developments in the field and further information on topics covered in the book* Journal Club to encourage students to critically analyse the research literature* Molecular Modelling Exercises, with new exercises in Chem3D* New assignments to help students develop data analysis and problem solving skillsFor registered adopters of the book:* A test bank of additional multiple-choice questions, with links to relevant sections in the book* Answers to end-of-chapter questions.* Figures from the book, ready to download.* Power Point slides to accompany every chapter in the book., For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market?An Introduction to Medicinal Chemistry, sixth edition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Part one of the book introduces the principles of drug action via targets such as receptors and enzymes. The book goes on to explore how drugs work at the molecular level (pharmacodynamics), and the processes involved in ensuring a drugmeets its target (pharmacokinetics). Further sections cover the processes by which drugs are discovered and designed, and what has to happen before a drug can be made available to the public. The book concludes with a selection of current topics in medicinal chemistry, and a discussion of various key druggroups. The subject is brought to life throughout by engaging case studies highlighting particular drugs and the stories behind their discovery and development.The Online Resource Centre features: For students:· Multiple Choice Questions to support self-directed learning · Web articles describing recent developments in the field and further information on topics covered in the book· Journal Club to encourage students to critically analyse the research literature· Molecular Modelling Exercises, with new exercises in Chem3D· New assignments to help students develop data analysis and problem solving skillsFor registered adopters of the book:· A test bank of additional multiple-choice questions, with links to relevant sections in the book· Answers to end-of-chapter questions.· Figures from the book, ready to download.· Power Point slides to accompany every chapter in the book.
LC Classification Number
RS403
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