RNA: Life's Indispensable Molecule by James Darnell (1st Ed. 2011 Sealed HC)

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Artikelzustand
Neu: Neues, ungelesenes, ungebrauchtes Buch in makellosem Zustand ohne fehlende oder beschädigte ...
Features
Dust Jacket, Sealed
ISBN
9781936113194
Kategorie

Über dieses Produkt

Product Identifiers

Publisher
Cold Spring Harbor Laboratory Press
ISBN-10
1936113198
ISBN-13
9781936113194
eBay Product ID (ePID)
99635041

Product Key Features

Number of Pages
416 Pages
Publication Name
Rna: Life's Indispensable Molecule
Language
English
Subject
Life Sciences / Molecular Biology, Life Sciences / Biochemistry, Life Sciences / Evolution
Publication Year
2011
Type
Textbook
Author
James Darnell
Subject Area
Science
Format
Hardcover

Dimensions

Item Height
1.1 in
Item Weight
33.7 Oz
Item Length
9.3 in
Item Width
6.2 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2011-001258
Dewey Edition
22
Reviews
"At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and 'e" most of all 'e" his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon." 'e"RNA"Darnell's book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist 'e" next to other classics like Watson's Molecular Biology of the Gene, Kornberg's DNA Replication, and Judson's The Eighth Day of Creation." 'e"Joe Goldstein, UT Southwestern"Jim Darnell's career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the author's own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb..." 'e"The FASEB Journal"Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field." 'e"Choice"Darnell's book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Life's Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all." 'e"Joan A. Steitz in Science"Although we take the roles of RNA for granted, its history is not as well known as that of DNA. Perhaps it was long overdue for a stellar RNA researcher such as James Darnell to undertake such a challenge. The book he has written is as remarkable as his career....The highly detailed account along with a flawless sense of history, take the reader through a fascinating journey of several decades of discoveries and exciting findings in molecular biology. Darnell's very personal style makes this book enjoyable...After reading more than 400 pages of text, I was not exhausted. This book should be mandatory reading for advanced undergraduates and graduate students in biology and biochemistry. Even newly minted doctoral recipients could benefit from reviewing some key experiments..." 'e"CBE 'e" Life Sciences Education, "At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and most of all his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon." RNA "Darnell's book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist next to other classics like Watson's Molecular Biology of the Gene, Kornberg's DNA Replication, and Judson's The Eighth Day of Creation." Joe Goldstein, UT Southwestern "Jim Darnell's career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the author's own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb..." The FASEB Journal "Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field." Choice "Darnell's book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Life's Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all." Joan A. Steitz in Science "Although we take the roles of RNA for granted, its history is not as well known as that of DNA. Perhaps it was long overdue for a stellar RNA researcher such as James Darnell to undertake such a challenge. The book he has written is as remarkable as his career....The highly detailed account along with a flawless sense of history, take the reader through a fascinating journey of several decades of discoveries and exciting findings in molecular biology. Darnell's very personal style makes this book enjoyable...After reading more than 400 pages of text, I was not exhausted. This book should be mandatory reading for advanced undergraduates and graduate students in biology and biochemistry. Even newly minted doctoral recipients could benefit from reviewing some key experiments..." CBE Life Sciences Education, "At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and -- most of all -- his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon." --RNA "Darnell's book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist -- next to other classics like Watson's Molecular Biology of the Gene, Kornberg's DNA Replication, and Judson's The Eighth Day of Creation." --Joe Goldstein, UT Southwestern "Jim Darnell's career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the author's own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb..." --The FASEB Journal "Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field." --Choice "Darnell's book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Life's Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all." --Joan A. Steitz in Science "Although we take the roles of RNA for granted, its history is not as well known as that of DNA. Perhaps it was long overdue for a stellar RNA researcher such as James Darnell to undertake such a challenge. The book he has written is as remarkable as his career....The highly detailed account along with a flawless sense of history, take the reader through a fascinating journey of several decades of discoveries and exciting findings in molecular biology. Darnell's very personal style makes this book enjoyable...After reading more than 400 pages of text, I was not exhausted. This book should be mandatory reading for advanced undergraduates and graduate students in biology and biochemistry. Even newly minted doctoral recipients could benefit from reviewing some key experiments..." --CBE -- Life Sciences Education, "At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and most of all his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon." RNA "Darnell's book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist next to other classics like Watson's Molecular Biology of the Gene, Kornberg's DNA Replication, and Judson's The Eighth Day of Creation." Joe Goldstein, UT Southwestern "Jim Darnell's career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the author's own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb..." The FASEB Journal "Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field." Choice "Darnell's book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Life's Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all." Joan A. Steitz in Science, At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and most of all his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon.RNA Darnells book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist next to other classics like Watsons Molecular Biology of the Gene, Kornbergs DNA Replication, and Judsons The Eighth Day of Creation.Joe Goldstein, UT Southwestern Jim Darnells career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the authors own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb...The FASEB Journal Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field.Choice Darnells book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Lifes Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all.Joan A. Steitz in Science Although we take the roles of RNA for granted, its history is not as well known as that of DNA. Perhaps it was long overdue for a stellar RNA researcher such as James Darnell to undertake such a challenge. The book he has written is as remarkable as his career....The highly detailed account along with a flawless sense of history, take the reader through a fascinating journey of several decades of discoveries and exciting findings in molecular biology. Darnells very personal style makes this book enjoyable...After reading more than 400 pages of text, I was not exhausted. This book should be mandatory reading for advanced undergraduates and graduate students in biology and biochemistry. Even newly minted doctoral recipients could benefit from reviewing some key experiments...CBE Life Sciences Education, "At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and -- most of all -- his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon." --RNA"Darnell's book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist -- next to other classics like Watson's Molecular Biology of the Gene, Kornberg's DNA Replication, and Judson's The Eighth Day of Creation." --Joe Goldstein, UT Southwestern"Jim Darnell's career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the author's own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb..." --The FASEB Journal"Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field." --Choice"Darnell's book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Life's Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all." --Joan A. Steitz in Science"Although we take the roles of RNA for granted, its history is not as well known as that of DNA. Perhaps it was long overdue for a stellar RNA researcher such as James Darnell to undertake such a challenge. The book he has written is as remarkable as his career....The highly detailed account along with a flawless sense of history, take the reader through a fascinating journey of several decades of discoveries and exciting findings in molecular biology. Darnell's very personal style makes this book enjoyable...After reading more than 400 pages of text, I was not exhausted. This book should be mandatory reading for advanced undergraduates and graduate students in biology and biochemistry. Even newly minted doctoral recipients could benefit from reviewing some key experiments..." --CBE -- Life Sciences Education, "At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and DL most of all DL his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon." DLRNA"Darnell's book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist DL next to other classics like Watson's Molecular Biology of the Gene, Kornberg's DNA Replication, and Judson's The Eighth Day of Creation." DLJoe Goldstein, UT Southwestern"Jim Darnell's career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the author's own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb..." DLThe FASEB Journal"Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field." DLChoice"Darnell's book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Life's Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all." DLJoan A. Steitz in Science"Although we take the roles of RNA for granted, its history is not as well known as that of DNA. Perhaps it was long overdue for a stellar RNA researcher such as James Darnell to undertake such a challenge. The book he has written is as remarkable as his career....The highly detailed account along with a flawless sense of history, take the reader through a fascinating journey of several decades of discoveries and exciting findings in molecular biology. Darnell's very personal style makes this book enjoyable...After reading more than 400 pages of text, I was not exhausted. This book should be mandatory reading for advanced undergraduates and graduate students in biology and biochemistry. Even newly minted doctoral recipients could benefit from reviewing some key experiments..." DLCBE DL Life Sciences Education
Illustrated
Yes
Dewey Decimal
572.8/8
Table Of Content
Preface Author's Note: Pursuing RNA for More Than 50 Years Introduction 1. The Dawn of Molecular Biology: History of Macromolecules before RNA 2. RNA Connects Genes and Proteins: Ribosomes, tRNA, and Messenger RNA 3. After mRNA: The Genetic Code, Translation, and the Biochemistry of Controlled RNA Synthesis in Bacteria 4. Gene Expression in Mammalian Cells: Discovery of RNA Processing, Genes in Pieces, and New RNA Chemistry 5. Controlling mRNA: The Cell's Most Complicated Task 6. RNA and the Beginning of Life Sources Index
Synopsis
In RNA: Life's Indispensable Molecule, Jim Darnell provides a comprehensive and captivating account of RNA research, illuminated by his own life-long and celebrated engagement in the field. Darnell describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA-how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, and with the clarity expected from an accomplished textbook author, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up, and will particularly appeal to active investigators in RNA biology, educators of molecular biology and biochemistry, and science historians., In RNA: Life's Indispensable Molecule, Jim Darnell provides a comprehensive and captivating account of RNA research, illuminated by his own life-long and celebrated engagement in the field. Darnell describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA--how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, and with the clarity expected from an accomplished textbook author, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up, and will particularly appeal to active investigators in RNA biology, educators of molecular biology and biochemistry, and science historians.
LC Classification Number
QP623.D37 2011

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