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Methoden in der Molekularbiologie Ser.: Xenotransplantation: Methoden und...

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ISBN
9781617798443

Über dieses Produkt

Product Identifiers

Publisher
Humana Press
ISBN-10
1617798444
ISBN-13
9781617798443
eBay Product ID (ePID)
112582530

Product Key Features

Number of Pages
Xi, 335 Pages
Publication Name
Xenotransplantation : Methods and Protocols
Language
English
Subject
Surgery / Transplant, Life Sciences / Cell Biology
Publication Year
2012
Type
Textbook
Subject Area
Science, Medical
Author
Cristina Costa
Series
Methods in Molecular Biology Ser.
Format
Hardcover

Dimensions

Item Weight
30.3 Oz
Item Length
10 in
Item Width
7 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2012-936662
Dewey Edition
23
Reviews
From the reviews: "This is a methodological book aimed at describing specific topics in xenotransplantation. The purpose is to offer a resource to help those in the field of xenotransplantation or those new researchers interested in starting a career. Given the ongoing need for organs and the advances that could be made with successful xenotransplantation, this is a worthy goal. ... this is a thorough book on certain aspects of xenotransplantation, and its methodological approach to certain procedures is helpful to scientists just entering the field." (Erin C. Maynard, Doody's Book Reviews, September, 2012), From the reviews: This is a methodological book aimed at describing specific topics in xenotransplantation. The purpose is to offer a resource to help those in the field of xenotransplantation or those new researchers interested in starting a career. Given the ongoing need for organs and the advances that could be made with successful xenotransplantation, this is a worthy goal. … this is a thorough book on certain aspects of xenotransplantation, and its methodological approach to certain procedures is helpful to scientists just entering the field. (Erin C. Maynard, Doody's Book Reviews, September, 2012), From the reviews: "This book gives a comprehensive outline on xenotransplantation, with contributions from a wide range of experts in the field. ... The chapters are well-organised and sequenced, and the figures and tables complement the text very well. ... it is a well-edited text with a multitude of excellent references. ... useful as a reference in a research laboratory, and can be of potential interest to researchers of all grades and levels of expertise in this field." (Karwan Moutasim, Immunology News, May, 2013) "This is a methodological book aimed at describing specific topics in xenotransplantation. The purpose is to offer a resource to help those in the field of xenotransplantation or those new researchers interested in starting a career. Given the ongoing need for organs and the advances that could be made with successful xenotransplantation, this is a worthy goal. ... this is a thorough book on certain aspects of xenotransplantation, and its methodological approach to certain procedures is helpful to scientists just entering the field." (Erin C. Maynard, Doody's Book Reviews, September, 2012)
Series Volume Number
885
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
611.01816
Table Of Content
Xenotransplantation: An Overview of the Field.-Cloning and Expression Analyses of Pig Genes.-Basic Analyses of Proteins of Interest for Xenotransplantation.-Studies on Carbohydrate Xenoantigens.-Xenoantibodies and Complement Activity Determinations in Pig to Primate Xenotransplantation.-Studies on Coagulation Incompatibilities for Xenotransplantation.-Cellular Studies for in Vitro Modeling of Xenogeneic Immune Responses.-Production of Transgenic and Knock Out Pigs by Somatic Cell Nuclear Transfer.-Small Animal Models of Xenotransplantation.-Heart Xenotransplantation in Primate Models.-Xenogeneic Lung Transplantation Models.-Thymic Transplantation in Pig-to-nonhuman Primates for the Induction of Tolerance Across Xenogeneic Barriers.-Isolation of Porcine Pancreatic Islets for Xenotransplantation.-Pig Neural Cells Derived from Foetal Mesencephalon as Cell Source for Intracerebral Xenotransplantation.-Hepatocyte Xenotransplantation.-In Vitro Repair Model of Focal Articular Cartilage Defects in Humans.-Potential Zoonotic Infection of PERV in Xenotransplantation.-Ethical and Regulatory Issues for Clinical Trials in Xenotransplantation.-Some Ethical, Social and Legal Considerations of Xenotransplantation.
Synopsis
In this book, experts study characterizations of xenogeneic interactions at the cellular and molecular levels and describe the use of relevant small-animal and pig-to-primate models. It also covers related ethical and legal considerations., Despite many technological challenges faced by the xenotransplantation field, many major advances have been made in the last two decades. The field seeks to overcome the limitations and difficulties in organ procurement, which also apply to human cells and tissues, and facilitate the development of new therapies based on cell and engineered-tissue. Xenogeneic cells are simpler than solid organs and seem to pose less hurdles to attain long-term graft survival. In, Xenotransplantation: Methods and Protocols expert researchers study characterizations of xenogeneic interactions at the cellular and molecular levels and describe the use of relevant small-animal and pig-to-primate models. Related ethical and legal considerations are also covered. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Xenotransplantation: Methods and Protocols aids scientists in continuing to study xenotransplantation and its multiple aspects., Despite many technological challenges faced by the xenotransplantation field, many major advances have been made in the last two decades. The field seeks to overcome the limitations and difficulties in organ procurement, which also apply to human cells and tissues, and facilitate the development of new therapies based on cell and engineered-tissue. Xenogeneic cells are simpler than solid organs and seem to pose less hurdles to attain long-term graft survival. In, Xenotransplantation: Methods and Protocols expert researchers study characterizations of xenogeneic interactions at the cellular and molecular levels and describe the use of relevant small-animal and pig-to-primate models. Related ethical and legal considerations are also covered. Written in the highly successful Methods in Molecular Biology (tm) series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Xenotransplantation: Methods and Protocols aids scientists in continuing to study xenotransplantation and its multiple aspects., 1. Xenotransplantation: An Overview of the Field Veronica Tisato and Emanuele Cozzi 2. Cloning and Expression Analyses of Pig Genes Mireia Uribe-Herranz and Cristina Costa 3. Basic Analyses of Proteins of Interest for Xenotransplantation Mireia Uribe-Herranz and Cristina Costa 4. Studies on Carbohydrate Xenoantigens Dale Christiansen, Effie Mouhtouris, Paul A. Ramsland, and Mauro S. Sandrin 5. Xenoantibodies and Complement Activity Determinations in Pig to Primate Xenotransplantation Nieves Doménech 6. Studies on Coagulation Incompatibilities for Xenotransplantation Cristiana Bulato, Claudia Radu, Paolo Simioni 7. Cellular Studies for in Vitro Modeling of Xenogeneic Immune Responses Roberta Sommaggio, Magdiel Pérez-Cruz, and Cristina Costa 8. Production of Transgenic and Knock Out Pigs by Somatic Cell Nuclear Transfer Angelica M. Giraldo, Suyapa Ball, Kenneth R. Bondioli 9. Small Animal Models of Xenotransplantation Hao Wang 10. Heart Xenotransplantation in Primate Models Johannes Postrach, Andreas Bauer, Michael Schmoeckel, Bruno Reichart, and Paolo Brenner 11. Xenogeneic Lung Transplantation Models Lars Burdorf, Agnes M. Azimzadeh and Richard N. Pierson III 12. Thymic Transplantation in Pig-to-nonhuman Primates for the Induction of Tolerance Across Xenogeneic Barriers Kazuhiko Yamada and Joseph Scalea 13. Isolation of Porcine Pancreatic Islets for Xenotransplantation Karin Ulrichs, Sibylle Eber, Bianca Schneiker, Sabine Gahn, Armin Strau , Vasiliy Moskalenko, Irina Chodnevskaja 14. Pig Neural Cells Derived from Foetal Mesencephalon as Cell Source for Intracerebral Xenotransplantation Xavier Lévêque, Véronique Nerrière-Daguin, Isabelle Neveuand Philippe Naveilhan 15. Hepatocyte Xenotransplantation Katia R. F. Lima-Quaresma, Andre Gustavo Bonavita, Matheus Kafuri Cytrangulo, Marcelo Alves Pinto, and Luiz Anastácio Alves 16. In Vitro Repair Model of Focal Articular Cartilage Defects in Humans Díaz Prado SM, Fuentes-Boquete IM, Blanco FJ 17. Potential Zoonotic Infection of PERV in Xenotransplantation Giada Mattiuzzo, Yashuhiro Takeuchi, Linda Scobie 18. Ethical and Regulatory Issues for Clinical Trials in Xenotransplantation Jorge Guerra González 19. Some Ethical, Social and Legal Considerations of Xenotransplantation María Jorqui Azofra and Carlos María Romeo Casabona
LC Classification Number
QH573-671

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