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Artikelmerkmale
- Artikelzustand
- ISBN
- 9780128001400
Über dieses Produkt
Product Identifiers
Publisher
Elsevier Science & Technology
ISBN-10
0128001402
ISBN-13
9780128001400
eBay Product ID (ePID)
217031245
Product Key Features
Number of Pages
328 Pages
Language
English
Publication Name
Epigenomics in Health and Disease
Publication Year
2015
Subject
Life Sciences / Molecular Biology, Embryology, Life Sciences / Genetics & Genomics
Type
Textbook
Subject Area
Science, Medical
Format
Hardcover
Dimensions
Item Length
9 in
Item Width
6 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2015-949020
Dewey Edition
23
Illustrated
Yes
Dewey Decimal
572.8/65
Table Of Content
Preface 1. The Role of the Genetic Code in the DNA Methylation Landscape Formation 2. DNA Methylation Microarrays 3. Ultra Deep Sequencing of Bisulfite Modified DNA 4. Bioinformatics Tools in Epigenomic Studies 5. Genome-Wide DNA Methylation Changes During Aging 6. The Dynamics of Histone Modifications During Aging 7. The DNA Methylomes of Cancer 8. Non-coding RNA Regulation of Health and Disease 9. Genome-Wide Epigenetic Studies in Neurological Diseases 10. Epigenetic Deregulation in Autoimmune Disease 11. Genome-Wide DNA and Histone Modification Studies in Metabolic Disease 12. Epigenomic Studies in Epidemiology 13. Clinical Applications of Epigenomics
Synopsis
Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications to the genetic material of human cells. With coverage pertinent to both basic biology and translational research, the book will be of particular interest for medical and bioscience researchers and students seeking current translational knowledge in epigenesis and epigenomics. Coverage includes the latest findings on epigenome-wide research in disease-based profiling, epidemiological implications, epigenome-wide epigenetic studies, the cancer epigenome, and other pervasive disease categories. Presents critical reviews that provide the means for reviewing and analyzing the epigenome as a whole, also discussing its translational potential Combines basic epigenomic knowledge with methodological and biostatistical topics related to technology and data analysis Includes coverage of relatively new topics, including DNA methylation dynamics during development and differentiation, genome-wide histone post-translational modifications during development and differentiation, and genome-wide DNA methylation changes during aging, Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications to the genetic material of human cells. With coverage pertinent to both basic biology and translational research, the book will be of particular interest for medical and bioscience researchers and students seeking current translational knowledge in epigenesis and epigenomics. Coverage includes the latest findings on epigenome-wide research in disease-based profiling, epidemiological implications, epigenome-wide epigenetic studies, the cancer epigenome, and other pervasive disease categories.
LC Classification Number
QH450
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