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Ecto-ATPasen - 9781461377290
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Artikelmerkmale
- Artikelzustand
- Book Title
- Ecto-ATPases
- ISBN
- 9781461377290
- Publication Year
- 2012
- Type
- Textbook
- Format
- Paperback
- Language
- English
- Publication Name
- Ecto-Atpases: Recent Progress on Structure and Function
- Item Height
- 254 mm
- Publisher
- Springer-Verlag New York Inc.
- Subject
- Chemistry, Botany, Biology
- Item Weight
- 596 g
- Item Width
- 178 mm
- Number of Pages
- 294 Pages
Über dieses Produkt
Product Information
It has been known for almost 50 years that many cells carry enzymes that hydro- lyze extracellular ATP, and the term ecto-ATPase was used first by Engelhardt 40 years ago. But until the end of the 1970's, the idea of an ATPase with its ATP hydrolyzing site on the outside of the cell membrane was met with substantial skepticism since it was thought that ATP was strictly intracellular. Nevertheless, ecto-ATPase activity was dem- onstrated using a variety of intact cells. Most ecto-ATPase(s) exhibited three common 2 characteristics: 1) activation by either Ca + or Mg2+, 2) insensitivity to the commonly used inhibitors ofF-type, P-type, and V-type ATPases, and 3) ability to hydrolyze nucleo- side triphosphates and often nucleoside diphosphates as well. At the same time, the dominant ATPase activity in many plasma membrane preparations was shown to be dis- tinct from the ion-pump ATPases, but had similar enzymatic properties as the ecto-AT- Pase(s). Thus the term E-type ATPase activity has been proposed for ATPase activity exhibiting these characteristics, and it is assumed that all ecto-ATPases are E-type AT- Pases. The converse is not true, however, since soluble E-type ATPases were shown to ex- sist in plants, microorganisms, and the saliva of blood sucking insects. These enzymes could be easily purified, and exhibited very high specific activity.
Product Identifiers
Publisher
Springer-Verlag New York Inc.
ISBN-13
9781461377290
eBay Product ID (ePID)
148984863
Product Key Features
Number of Pages
294 Pages
Language
English
Publication Name
Ecto-Atpases: Recent Progress on Structure and Function
Publication Year
2012
Subject
Chemistry, Botany, Biology
Type
Textbook
Format
Paperback
Dimensions
Item Height
254 mm
Item Weight
596 g
Item Width
178 mm
Additional Product Features
Editor
Terence L. Kirley, Aileen F. Knowles, Liselotte Plesner
Country/Region of Manufacture
United States
Artikelbeschreibung des Verkäufers
Rechtliche Informationen des Verkäufers
USt-IdNr.:
- GB 976952259
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