SEX AND THE ORIGINS OF DEATH von William R. Clark - Hardcover **Neuwertig**
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SEX AND THE ORIGINS OF DEATH von William R. Clark - Hardcover **Neuwertig**
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eBay-Artikelnr.:336108111310
Artikelmerkmale
- Artikelzustand
- Neuwertig
- Hinweise des Verkäufers
- ISBN-10
- 019510644X
- Publication Name
- Oxford University Press
- Type
- Hardcover
- ISBN
- 9780195106442
Über dieses Produkt
Product Identifiers
Publisher
Oxford University Press, Incorporated
ISBN-10
019510644X
ISBN-13
9780195106442
eBay Product ID (ePID)
11038259040
Product Key Features
Book Title
Sex and the Origins of Death
Number of Pages
208 Pages
Language
English
Topic
Life Sciences / Cell Biology, Life Sciences / Biology
Publication Year
1996
Illustrator
Yes
Genre
Science
Format
Hardcover
Dimensions
Item Height
0.8 in
Item Weight
13.4 Oz
Item Length
8.6 in
Item Width
5.8 in
Additional Product Features
Intended Audience
Trade
LCCN
96-011753
Reviews
"In this very comprehensive book, William Clark uses a lively and engagingstyle to develop an interesting hypothesis."--American Scientist, "Anyone who reckons that science writing is dry stuff may find theiroutlook broadened by this little book about the biology of death."-ewScientist, "Anyone who reckons that science writing is dry stuff may find their outlook broadened by this little book about the biology of death."--ew Scientist, "Traversing the microcosm where sex is easily untangled from reproduction,Clark's book, an exciting voyage to the center of death, is full of life."--LynnMargulis, Distinguished University Professor, University of Massachusetts,Amherst, "Immunologist Clark looks at cell death...and explores 'programmed cell death'--how and why particular cells commit suicide, ultimately causing our bodies to age and die."--Natural History, "Advanced life forms are condemned to certain death. It is the ultimatesacrifice we make for the potential improvement of the biotic commonweal. Thisis a hard truth, and UCLA cell biologist William Clark does an exemplary jobexplaining and apologizing for it.... An intellectually exciting and oftenlyrical trip to the strange zone where philosophy meets phylogeny."--TheWashington Post Book World, "In this very comprehensive book, William Clark uses a lively and engaging style to develop an interesting hypothesis."--American Scientist, "Clark explores some of the social, philosophical, and religious aspects of human beings in his lucid, thought-provoking work that concludes that, in the long view, humans differ not at all from other living creatures."--Booklist, "Immunologist Clark looks at cell death...and explores 'programmed celldeath'--how and why particular cells commit suicide, ultimately causing ourbodies to age and die."--Natural History, "Anyone who reckons that science writing is dry stuff may find their outlook broadened by this little book about the biology of death."-ew Scientist, "Traversing the microcosm where sex is easily untangled from reproduction, Clark's book, an exciting voyage to the center of death, is full of life."--Lynn Margulis, Distinguished University Professor, University of Massachusetts, Amherst, "Clark explores some of the social, philosophical, and religious aspectsof human beings in his lucid, thought-provoking work that concludes that, in thelong view, humans differ not at all from other livingcreatures."--Booklist, "Advanced life forms are condemned to certain death. It is the ultimate sacrifice we make for the potential improvement of the biotic commonweal. This is a hard truth, and UCLA cell biologist William Clark does an exemplary job explaining and apologizing for it.... An intellectually excitingand often lyrical trip to the strange zone where philosophy meets phylogeny."--The Washington Post Book World
Dewey Edition
20
Dewey Decimal
574.8765
Synopsis
Death, for bacteria, is not inevitable. Protect a bacterium from predators, and provide it with adequate food and space to grow, and it would continue living--and reproducing asexually--forever. But a paramecium (a slightly more advanced single-cell organism), under the same ideal conditions, would stop dividing after about 200 generations--and die. Death, for paramecia and their offspring, is inevitable. Unless they have sex. If at any point during that 200 or so generations, two of the progeny of our paramecium have sex, their clock will be reset to zero. They and their progeny are granted another 200 generations. Those who fail to have sex eventually die. Immortality for bacteria is automatic; for all other living beings--including humans--immortality depends on having sex. But why is this so? Why must death be inevitable? And what is the connection between death and sexual reproduction? In Sex and the Origins of Death, William R. Clark looks at life and death at the level of the cell, as he addresses such profound questions as why we age, why death exists, and why death and sex go hand in hand. Clark reveals that there are in fact two kinds of cell death--accidental death, caused by extreme cold or heat, starvation, or physical destruction, and "programmed cell death," initiated by codes embedded in our DNA. (Bacteria have no such codes.) We learn that every cell in our body has a self-destruct program embedded into it and that cell suicide is in fact a fairly commonplace event. We also discover that virtually every aspect of a cell's life is regulated by its DNA, including its own death, that the span of life is genetically determined (identical twins on average die 36 months apart, randomly selected siblings 106 months apart), that human tissue in culture will divide some 50 times and then die (an important exception being tumor cells, which divide indefinitely). But why do our cells have such programs? Why must we die? To shed light on this question, Clark reaches far back in evolutionary history, to the moment when "inevitable death" (death from aging) first appeared. For cells during the first billion years, death, when it occurred, was accidental; there was nothing programmed into them that said they must die. But fierce competition gradually led to multicellular animals--size being an advantage against predators--and with this change came cell specialization and, most important, germ cells in which reproductive DNA was segregated. When sexual reproduction evolved, it became the dominant form of reproduction on the planet, in part because mixing DNA from two individuals corrects errors that have crept into the code. But this improved DNA made DNA in the other (somatic) cells not only superfluous, but dangerous, because somatic DNA might harbor mutations. Nature's solution to this danger, Clark concludes, was programmed death--the somatic cells must die. Unfortunately, we are the somatic cells. Death is necessary to exploit to the fullest the advantages of sexual reproduction. In Sex and the Origins of Death, William Clark ranges far and wide over fascinating terrain. Whether describing a 62-year-old man having a major heart attack (and how his myocardial cells rupture and die), or discussing curious life-forms that defy any definition of life (including bacterial spores, which can regenerate after decades of inactivity, and viruses, which are nothing more than DNA or RNA wrapped in protein), this brilliant, profound volume illuminates the miraculous workings of life at its most elemental level and finds in these tiny spaces the answers to some of our largest questions., In Sex and the Origins of Death, William R. Clark looks at life and death at the level of the cell, as he addresses such profound questions as why we age, why death exists, and why death and sex go hand in hand. Whether describing a 62 year old man having a major heart attack (and how his myocardial cells rupture and die), or discussing curious life forms that defy any definition of life (including bacterial spores, which can regenerate after decades of inactivity, and viruses, which are nothing more than DNA or RNA wrapped in protein), this brilliant, profound volume illuminates the miraculous workings of life at its most elemental level and finds in these tiny spaces the answers to some of our largest questions., Death, for bacteria, is not inevitable. Protect a bacterium from predators, and provide it with adequate food and space to grow, and it would continue living--and reproducing asexually--forever. But a paramecium (a slightly more advanced single-cell organism), under the same ideal conditions, would stop dividing after about 200 generations--and die. Death, for paramecia and their offspring, is inevitable. Unless they have sex. If at any point during that 200 or so generations, two of the progeny of our paramecium have sex, their clock will be reset to zero. They and their progeny are granted another 200 generations. Those who fail to have sex eventually die. Immortality for bacteria is automatic; for all other living beings--including humans--immortality depends on having sex. But why is this so? Why must death be inevitable? And what is the connection between death and sexual reproduction? In Sex and the Origins of Death , William R. Clark looks at life and death at the level of the cell, as he addresses such profound questions as why we age, why death exists, and why death and sex go hand in hand. Clark reveals that there are in fact two kinds of cell death--accidental death, caused by extreme cold or heat, starvation, or physical destruction, and "programmed cell death," initiated by codes embedded in our DNA. (Bacteria have no such codes.) We learn that every cell in our body has a self-destruct program embedded into it and that cell suicide is in fact a fairly commonplace event. We also discover that virtually every aspect of a cell's life is regulated by its DNA, including its own death, that the span of life is genetically determined (identical twins on average die 36 months apart, randomly selected siblings 106 months apart), that human tissue in culture will divide some 50 times and then die (an important exception being tumor cells, which divide indefinitely). But why do our cells have such programs? Why must we die? To shed light on this question, Clark reaches far back in evolutionary history, to the moment when "inevitable death" (death from aging) first appeared. For cells during the first billion years, death, when it occurred, was accidental; there was nothing programmed into them that said they must die. But fierce competition gradually led to multicellular animals--size being an advantage against predators--and with this change came cell specialization and, most important, germ cells in which reproductive DNA was segregated. When sexual reproduction evolved, it became the dominant form of reproduction on the planet, in part because mixing DNA from two individuals corrects errors that have crept into the code. But this improved DNA made DNA in the other (somatic) cells not only superfluous, but dangerous, because somatic DNA might harbor mutations. Nature's solution to this danger, Clark concludes, was programmed death--the somatic cells must die. Unfortunately, we are the somatic cells. Death is necessary to exploit to the fullest the advantages of sexual reproduction. In Sex and the Origins of Death , William Clark ranges far and wide over fascinating terrain. Whether describing a 62-year-old man having a major heart attack (and how his myocardial cells rupture and die), or discussing curious life-forms that defy any definition of life (including bacterial spores, which can regenerate after decades of inactivity, and viruses, which are nothing more than DNA or RNA wrapped in protein), this brilliant, profound volume illuminates the miraculous workings of life at its most elemental level and finds in these tiny spaces the answers to some of our largest questions.
LC Classification Number
QH671.C56 1996
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- r***c (1305)- Bewertung vom Käufer.Letzter MonatBestätigter KaufOutstanding seller. Extremely satisfied with my order.
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