|Eingestellt in Kategorie:
Ähnlichen Artikel verkaufen?

Neue Therapien zur Vorbeugung oder Heilung von Hörstörungen, Hardcover von Pucheu, Syl...

Artikelzustand:
Neuwertig
2 verfügbar
Preis:
US $123,90
Ca.CHF 112,14
Versand:
Kostenlos Economy Shipping. Weitere Detailsfür Versand
Standort: Jessup, Maryland, USA
Lieferung:
Lieferung zwischen Mi, 22. Mai und Mo, 3. Jun nach 43230 bei heutigem Zahlungseingang
Liefertermine - wird in neuem Fenster oder Tab geöffnet berücksichtigen die Bearbeitungszeit des Verkäufers, die PLZ des Artikelstandorts und des Zielorts sowie den Annahmezeitpunkt und sind abhängig vom gewählten Versandservice und dem ZahlungseingangZahlungseingang - wird ein neuem Fenster oder Tab geöffnet. Insbesondere während saisonaler Spitzenzeiten können die Lieferzeiten abweichen.
Rücknahmen:
14 Tage Rückgabe. Käufer zahlt Rückversand. Weitere Details- Informationen zu Rückgaben
Zahlungen:
     

Sicher einkaufen

eBay-Käuferschutz
Geld zurück, wenn etwas mit diesem Artikel nicht stimmt. 

Angaben zum Verkäufer

Angemeldet als gewerblicher Verkäufer
Der Verkäufer ist für dieses Angebot verantwortlich.
eBay-Artikelnr.:385596968989
Zuletzt aktualisiert am 27. Mär. 2024 07:12:47 MEZAlle Änderungen ansehenAlle Änderungen ansehen

Artikelmerkmale

Artikelzustand
Neuwertig: Buch, das wie neu aussieht, aber bereits gelesen wurde. Der Einband weist keine ...
Book Title
New Therapies to Prevent or Cure Auditory Disorders
ISBN
9783030404123
Publication Year
2020
Type
Textbook
Format
Hardcover
Language
English
Publication Name
New Therapies to Prevent or Cure Auditory Disorders
Author
Kelly E. Radziwon
Item Length
9.3in
Publisher
Springer International Publishing A&G
Item Width
6.1in
Item Weight
16.4 Oz
Number of Pages
VII, 186 Pages

Über dieses Produkt

Product Information

Hearing loss is the most common form of sensory impairment in humans, affecting 360 million persons worldwide. In parallel, tinnitus disorder, the perception of a phantom sound often described as a ringing or buzzing, affects around 10-15% of the general population and interferes with daily life. Hyperacusis, defined as a hypersensitivity to moderate-intensity sounds often co-occurs with tinnitus suggesting a common mechanism of dysfunction for these two perceptual disorders. Whereas some drug candidates are in the process of being developed, nowadays no effective treatment exists to cure hearing loss and tinnitus. The topic of this book was selected with the goal of emphasizing mechanisms that induce hearing loss and tinnitus which lead the selection of promising targets for hearing disorder treatment. Hair cells (HC) are the sensory cells of the inner ear required for both auditory and vestibular functions in all vertebrates. HC are progressively lost during ageing and they are in addition sensitive to physical and acoustic traumas, infectious diseases and chemicals present in commonly used treatments such as anticancer, antimalarial or antibiotics. As adult mammals--including humans--cannot regenerate dead HC, all the possible injury could result in irreversible and permanent hearing loss. It has been shown, however, that a limited capacity to regenerate HC exists in mouse at an early stage of development. The regenerative capacity of HC then appears simply "repressed" in adult mammals, and one could expect it will be possible to re-activate it with an appropriate therapeutic approach which is still to be defined. Immune-mediated inner ear disease has been introduced and accepted as one SNHL pathophysiology; it responds to immunosuppressive therapy and is one of the few reversible forms of bilateral SNHL. Macrophages are always present in the spiral ligament of the lateral wall and are activated in response to various types of stimuli, including noise exposure, ischemia, mitochondrial damage, and surgical stress. Recent studies have also revealed another type of immune cell, called perivascular melanocyte-like macrophages (PVM/Ms), in the stria vascularis. The book will include a review of inflammatory/immune cells in the cochlear lateral wall, the pathways involved in cochlear damage and their potential as therapeutic targets. The final chapter provides an overview of current animal model of tinnitus and hyperacusis. Nowadays no effective treatment exists to cure tinnitus and hyperacusis. One major obstacle to arises from the fact that tinnitus is a subjective phenomenon, the only possible diagnosis relies on self-reports of the subjects. The main constraint of the use of animal models is the subjective character of tinnitus. This chapter describe the advancement in animal models which play an important role in revealing the underlying mechanisms and treatment for tinnitus and hyperacusis.

Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-10
3030404129
ISBN-13
9783030404123
eBay Product ID (ePID)
25038414967

Product Key Features

Author
Kelly E. Radziwon
Publication Name
New Therapies to Prevent or Cure Auditory Disorders
Format
Hardcover
Language
English
Publication Year
2020
Type
Textbook
Number of Pages
VII, 186 Pages

Dimensions

Item Length
9.3in
Item Width
6.1in
Item Weight
16.4 Oz

Additional Product Features

Number of Volumes
1 Vol.
Lc Classification Number
Rc321-580
Table of Content
Life-style intervention to prevent age-related hearing loss : calorie restriction Noise-induced hearing loss and drug therapy ; basic and translational science. Review of ototoxic drugs and treatment strategies for reducing hearing loss. Approaches to regenerate hair cells and spiral ganglion neuron in the inner ear. Immune system and macrophage activation in the cochlea: implication for therapeutic intervention Preclinical animal Behavioral models of hyperacusis and Loudness recruitment New automatic and robust measures to evaluate hearing loss and tinnitus in preclinical models
Copyright Date
2020
Topic
Neuroscience, Otorhinolaryngology
Illustrated
Yes
Genre
Medical

Artikelbeschreibung des Verkäufers

Great Book Prices Store

Great Book Prices Store

96,8% positive Bewertungen
1.2 Mio. Artikel verkauft
Shop besuchenKontakt
Antwortet meist innerhalb 24 Stunden

Detaillierte Verkäuferbewertungen

Durchschnitt in den letzten 12 Monaten

Genaue Beschreibung
4.9
Angemessene Versandkosten
5.0
Lieferzeit
4.9
Kommunikation
4.8
Angemeldet als gewerblicher Verkäufer

Verkäuferbewertungen (340'290)

e***e (2012)- Bewertung vom Käufer.
Letzter Monat
Bestätigter Kauf
Secure packaging, Swift delivery
a***9 (22)- Bewertung vom Käufer.
Letzter Monat
Bestätigter Kauf
This is NOT the book I ordered. I was sent the 2012 copy & not the 1987 copy that I thought I was ordering per the picture. This is NOT the picture that was posted of the book. I will keep the book but I do not appreciate receiving a different copy. I consider this to be dishonest of the seller. The only thing correct is that the book is new.
s***_ (254)- Bewertung vom Käufer.
Letzter Monat
Bestätigter Kauf
Good transaction. Thanks