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Natural Computing Ser.: Modelling in Molecular Biology by Grzegorz Rozenberg HC
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eBay-Artikelnr.:396981342415
Artikelmerkmale
- Artikelzustand
- ISBN
- 9783540407997
Über dieses Produkt
Product Identifiers
Publisher
Springer Berlin / Heidelberg
ISBN-10
3540407995
ISBN-13
9783540407997
eBay Product ID (ePID)
30234855
Product Key Features
Number of Pages
X, 305 Pages
Publication Name
Modelling in Molecular Biology
Language
English
Publication Year
2004
Subject
Life Sciences / Molecular Biology, Life Sciences / Biochemistry, Computer Science, Life Sciences / Biology, Discrete Mathematics
Type
Textbook
Subject Area
Mathematics, Computers, Science
Series
Natural Computing Ser.
Format
Hardcover
Dimensions
Item Weight
49 Oz
Item Length
9.3 in
Item Width
6.1 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2004-106401
Dewey Edition
22
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
572.8/01/13
Table Of Content
Stoichiometric Foundation of Large-Scale Biochemical System Analysis.- Modelling Stochastic Clonal Interference.- Software Verification of Biomolecular Systems.- Kinetic Modelling as a Modern Technology to Explore and Modify Living Cells.- Modelling Gene Assembly in Ciliates.- Towards Molecular Programming -- a Personal Report on DNA8 and Molecular Computing.- Molecular Information Theory: Solving the Mysteries of DNA.- Formal Modelling of C. elegans Development. A Scenario-Based Approach.- P Systems with Symport/Antiport Rules. A Survey.- Mathematical Modelling of the Immune System.- The ?-calculus as an Abstraction for Biomolecular Systems.- The Topology of Evolutionary Biology.- Models of Genome Evolution.
Synopsis
The key idea underlying this book is the notion that molecules and cells, which constitute the basic building blocks of all living systems, are too complex to be fully understood by the human mind without the aid of a good model and a computer., This volume is based on the workshop"Modelling in Molecular Biology" that tookplacein2002inSingapore. Themaingoaloftheworkshopwastopresent models/methods used in solving some fundamental problems in biosciences. The volume consists of a selection of papers presented at the workshop as well as of some other papers that are included so that the presentation of the theme of the workshop is broader and more balanced. As a matter of fact we feel that the collection of papers comprising this volume represents a wide spectrum of quite diverse ideas and trends. The paper by D. A. Beard et al. explores the common thesis that und- standingthebehaviouroflargeinteractingsystemsofmanyenzymesandre- tants underlies the modelling and simulation of whole-cell systems. Moreover, the models need to represent the basic stoichiometry, with balanced che- cal reactions and the conservation of mass, energy and charge. The authors discuss the stoichiometric and then kinetic details of approaches to modelling and simulation of biochemical systems. P. R. A. Campos et al. are concerned with models of evolution and adaptation (which is essential for precise - derstanding of molecular phylogeny). In particular, their paper is concerned with the rate of adaptation of asexual organisms(which is important because it in?uences the speed of the assumed molecular clock). It is known that for such organisms the rate of adaptation does not steadily increase with the - creasing rate of advantageous mutations, and this paper studies the mutual interference of two advantageous mutants that are each initially present in only a single organism., This volume is based on the workshop"Modelling in Molecular Biology" that tookplacein2002inSingapore. Themaingoaloftheworkshopwastopresent models/methods used in solving some fundamental problems in biosciences. The volume consists of a selection of papers presented at the workshop as well as of some other papers that are included so that the presentation of the theme of the workshop is broader and more balanced. As a matter of fact we feel that the collection of papers comprising this volume represents a wide spectrum of quite diverse ideas and trends. The paper by D. A. Beard et al. explores the common thesis that und- standingthebehaviouroflargeinteractingsystemsofmanyenzymesandre- tants underlies the modelling and simulation of whole-cell systems. Moreover, the models need to represent the basic stoichiometry, with balanced che- cal reactions and the conservation of mass, energy and charge. The authors discuss the stoichiometric and then kinetic details of approaches to modelling and simulation of biochemical systems. P. R. A. Campos et al. are concerned with models of evolution and adaptation (which is essential for precise - derstanding of molecular phylogeny). In particular, their paper is concerned with the rate of adaptation of asexual organisms(which is important because it in'uences the speed of the assumed molecular clock). It is known that for such organisms the rate of adaptation does not steadily increase with the - creasing rate of advantageous mutations, and this paper studies the mutual interference of two advantageous mutants that are each initially present in only a single organism., The key idea underlying this book is the notion that molecules and cells, which constitute the basic building blocks of all living systems, are too complex to be fully understood by the human mind without the aid of a good model and a computer. Therefore, the modeling of living systems and processes is mandatory in order to gain a complete description and understanding. The authors present new mathematical and computational models as well as statistical methods for the solution of fundamental problems in the biosciences.
LC Classification Number
QD415-436
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